Colorado voters approved Proposition 122, the Natural Medicine Health Act, in November 2022. The state has a licensed program in which adults 21 and older can receive services at licensed healing centers with licensed facilitators. Psilocybin remains a Schedule I controlled substance under federal law.
Colorado voters approved Proposition 122, the Natural Medicine Health Act, in November 2022. The state has a licensed program in which adults 21 and older can receive services at licensed healing centers with licensed facilitators. Psilocybin remains a Schedule I controlled substance under federal law.
Keep the scope clear
This guide discusses Colorado's licensed services only. It does not explain obtaining psilocybin outside that program or give advice about personal legal circumstances. State-program licensing should not be described as changing federal status.
Use official records
Consult the Colorado Natural Medicine Division and the healing center license lookup. This article gives educational information, not legal or medical advice.
If you are in crisis, call or text 988.
Official sources
Sources checked 7 November 2026: Colorado Natural Medicine Division · Healing center license lookup · Natural Medicine Licensure Rules, 4 CCR 755-1.
Federal status: 21 CFR 1308.11, Schedule I.
This page is informational and is not medical advice.